Ezra 2:2–67 (ESV)

2 They came with Zerubbabel, Jeshua, Nehemiah, Seraiah, Reelaiah, Mordecai, Bilshan, Mispar, Bigvai, Rehum, and Baanah.The number of the men of the people of Israel:

There is no one who is insignificant. I remember when I was in seminary, one of my professors made this point and it caused me great joy, comfort, and encouragement. He said, most of you in my class here are going to be insignificant for the rest of your life. Most of you are going to be pastors and you are going to be insignificant according to what the world says. Get used to it. Accept that in the world's eyes you are not going to be significant; you are not going to be a John Calvin or a Luther, or whatever. You are going to be serving a small church and you are going to be struggling through in the ministry and may not have great impact on thousands and millions of people. Get used to it. But think about this, not a single one of these people were insignificant to God and you are not insignificant to God. Though you may look at your life and though you may say, well, I do not really see that God will be using me like I imagined I would, or what I would like to be, you are not insignificant to God.

Why is it that the Bible talks about the Book of Life, and the name of the individual written in the Book? Because that individual is not insignificant, [but he/she] is significant to God. And so the Book of Life is not only there [for us] to say, well, yes, I want my name in the Book of Life so I [can] go to heaven and be with God all eternity, but also, my name is there because God writes it in. God causes it to be written in because I am significant to God. How do I know that? Because Jesus Christ came and died on the cross for my sake. I am significant to God. You are significant to God. And so we find again and again throughout the Scriptures, names of insignificant people.1

Michael Voytek