1. Amos 5:19 (ESV)
  2. Exposition

What is the significance of the lion, bear, and snake?

Amos 5:19 (ESV)

19 as if a man fled from a lion, and a bear met him, or went into the house and leaned his hand against the wall, and a serpent bit him.

The three examples given are all symbols of danger and they do not have a deeper spiritual meaning.