Their sinful desires are what destroys these people. Acting according to their sinful nature, they gain only moral corruption for themselves.1 Persevering in sin, they harden their hearts to God and so—like the examples mentioned in Jude 5-8—the end result will be that these people are destroyed by God instead of receiving his mercy.2
10 But these people blaspheme all that they do not understand, and they are destroyed by all that they, like unreasoning animals, understand instinctively.